Author: Luca Povolo
Co-authors: Sebastiano Mariazzi, Luca Penasa, Ruggero Caravita, Sushil Sharma, Roberto Sennen Brusa
At the Anti-Matter Laboratory (AML) of the Department of Physics of the University of Trento a new positron beam is currently under development. It is being constructed for the production into vacuum of Positronium (Ps, the bound state of an electron and the positron,...
Author: Aleksander Khreptak
The main aim of the SIDDHARTA-2 experiment at the DAΦNE collider in the LNF-INFN (Italy) is to perform the high precision measurement of the kaonic deuterium exotic atom, which is formed when a negatively charged kaon (K−) is captured in a highly atomic excited state, replacing an electron [1,2].
To achieve this goal, a large area Silicon Drift Detectors...
Authors: Jakub Hajduga, Dose-3D Collaboration
As part of the Dose-3D project titled "Reconfigurable detector for measuring spatial distribution of radiation dose for applications in preparing individual patient treatment plans", in addition to the construction of the new type of phantom itself, it is necessary to develop high-end software for dose simulation, configuration and control of...
Author: Magdalena Goździuk
Co-authors: Bożena Zgardzińska, Taras Kavetskyy
Biosensors are devices widely used in many fields of medicine. Using biosensors we can detect biomarkers of pathological states. One of very popular biosensor types are enzymatic biosensors. The biggest advantage of enzymatic biosensor is detection of specific molecules depending on the enzyme used which is...
Authors: Mizuki Uenomachi, Kenji Shimazoe, Hiroyuki Takahashi
Positron emission tomography (PET) utilizes the coincidence detection of annihilation gamma-rays with energy of 511 keV produced after a positron-electron collision. The positron position can only be constrained on a line connecting the detection points because two annihilation gamma-rays emit at the opposite direction. On the...
Authors: Kamila Kalecińska, Dose-3D Collaboration
Medical data intelligent analysis is the part of TEAM NET
Dose3D Project “A Reconfigurable Detector for Measuring the Spatial Distribution of Radiation Dose for Applications in the Preparation of Individual Patient Treatment Plans”. The goal of the Dose3D consortium is to build a three-dimensional measurement system containing a detector...
Author: Barbara Kołodziej
Co-authors: Aleksandra Wrońska, Aleksandra Kaszlikowska, Mareike Profe, Ronja Hetzel , Barbara Beus, Magdalena Garbacz, Renata Kopeć
Proton therapy is a radiotherapy method which is superior to conventional radiotherapy performed with photons because of the achievable dose conformality. However, to fully benefit from the favorable dose-depth profile of the ion...
Author: Agata Tobola-Galus
Co-authors: Jan Swakoń, Paweł Olko
Purpose
In spatially fractionated proton therapy SFTP (proton grid therapy) the arrays of parallel and pencil proton beams generated by grid collimator are applied to reduce the impact of irradiation on healthy tissue. At the beam entrance the locally irradiated skin benefits from the ununiform profile of beam causing faster...
Author: Yannick Kuhl
Co-authors: Florian Mueller, Stephan Naunheim, David Schug, Volkmar Schulz
Introduction
Available clinical positron emission tomography (PET) systems commonly consist of one-layer segmented detector arrays with planar 2D gamma positioning. However, without 3D positioning in the additional depth-of-interaction (DOI) direction the system’s spatial resolution is reduced...
Author: Gabriela Łapkiewicz
Co-authors: Pawel Moskal, Szymon Niedźwiecki
G. Łapkiewicz1,2*, Sz. Niedźwiecki1,2, P. Moskal1,2, on behalf of J-PET collaboration
1Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Cracow, Poland
2Center for Theranostics, Jagiellonian University, Cracow, Poland
Phantoms used in PET technique, such as NEMA IEC allow for...
Author: Keyvan Tayefi Ardebili
Co-authors: Szymon Niedżwiecki , Paweł Moskal
Estimation of 511 keV gamma scatter fraction in WLS layer in Total Body J-PET
Keyvan Tayefi Ardebili1,2, Szymon Niedżwiecki 1,2, Paweł Moskal 1,2 on behalf of the J-PET collaboration.
1Faculty of Physics, Astronomy, and Applied Computer Science, Jagiellonian University, Łojasiewicza 11, 30-348 Kraków,...
Author: Shivani
Shivani1,2 On the behalf of J-PET collaboration
1Faculty of Physics and Applied Computer Science, Jagiellonian University, Cracow, Poland
2Center for Theranostics, Jagiellonian University, Poland
In both developing and developed countries, breast cancer is the top cause of mortality among women. Medical imaging plays an important role for breast cancer screening, for...
Author: Monika Szczepanek
Co-authors: Anna Telk, Ewa Stępień
Melanoma is the most aggressive skin cancer, difficult to treat when metastatic. It is also cancer that may become a candidate for Boron Neutron Capture Therapy (BNCT). BNCT is type of radiation therapy that employ the altered metabolism of cancer cells and additionally minimizes side effects. During treatment, the patient is...
Author: Katsiaryna Yankova
Co-authors: Bożena Zgardzińska, Bożena Jasińska, Marek Gorgol, Marcin Czop, Janusz Kocki
The HL-60 human acute promyelocytic leukemia cells obtained from the Clinical Genetics Department of Medical University in Lublin were investigated with the use of positron and positronium probes. The HL-60 cell line is a popular and convenient test object due to easy...
Author: Dr Magdalena Marzec
Co-authors: Carina Rząca, Ewa Stepien
Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS) is used to analyze biomolecules in tissues, cells and membranous structures. This type of mass spectrometry enables qualitative semi-native testing without the need for isolation, fixation or labelling of target elements with simultaneous 2D imaging. The analyzed mass...
Authors: Dominik Panek, Monika Szczepanek
Co-authors: Bartosz Leszczyński, Paweł Moskal, Ewa Stępień
Micro-computed tomography (micro-CT) is nowadays often used to examine biological samples. This technique, based on the attenuation of X-rays, is capable of achieving micrometric resolution. However, the challenge is to stain the samples in such a way that they will be opaque to the X-ray...
Authors: Wioleta Górska, DOSE-3D Collaboration
Radiotherapy aims to deliver a specific dose of radiation to the treated area, destroying the tumour. Thanks to the use of newer technologies and their continuous development, it is possible to very precisely deliver the planned doses of radiation to the treated areas, while reducing the exposure of healthy tissues to radiation. Undoubtedly,...
Author: Konrad Skórkiewicz
Co-authors: Anna Sowa-Staszczak, Kazimierz Łątka
Aim/Introduction: The aim of the study is to determine the appropriate value of the β parameter using the Q.Clear reconstruction algorithm in the imaging of patients with neuroendocrine tumors. Materials and Methods: The analysis concerned the measurements of the NEMA IEC Body Phantom, filled with Ga-68 gallium...
Author: Deepak Kumar
Co-author: Sushil Sharma
D. Kumar1,2,3, S. Sharma1,2,3 on behalf of the J-PET collaboration
1Faculty of Physics, Astronomy, and Applied Computer Science, Jagiellonian University, Poland.
2Total-Body Jagiellonian-PET Laboratory, Jagiellonian University, Kraków, Poland
3Center for Theranostics, Jagiellonian University, Cracow, Poland
e-mail:...
Authors: K. Dulski1,2 and M. Szczepanek1,2
1Institute of Physics, Jagiellonian University, Kraków, Poland
2Center for Theranostics, Jagiellonian University, Kraków, Poland
Cell cultures are a recognized model that helps understand interaction of cells with certain external factors, such as radiation or drugs [1,2]. In particular, characterizing the growth of a given cell line for a...
Author: K. Dulski on behalf of the J-PET collaboration
Positronium imaging is a promising new technique that can enhance the diagnostic capabilities of Positron Emission Tomography (PET), based on a new structural index derived from ortho-positronium interaction with the environment in which it annihilates [1,2]. A positronium (Ps) can be formed during a standard PET scan when a positron...
Authors: Munetaka Nitta, Giulio Lovatti, Kang Han Gyu, Rohgieh Haghani, Chiara Gianoli, Georgious Dedes, Andrea Zogular, Yamaya Taiga, Christoph Scheidenberger, Marco Durante, Peter Thirolf, Katia Paodi
We have been developing a high resolution small in-beam PET system in the framework of the project “Small animal Irradiation for Research in Molecular Image-guided radiation Oncology...
Kavya Valsan Eliyan, Juhi Raj, On Behalf of the J-PET Collaboration Jagiellonian University.
Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Kraków, Poland.
Theranostics Center, Jagiellonian University, Kraków, Poland.
Email: kavya.eliyan@doctoral.uj.edu.pl, juhi.raj@doctoral.uj.edu.pl
Interaction between electron-positron pair leads to direct...
Author: Neha Chug
Neha Chug1,2* on behalf of the J-PET Collaboration
1Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Krakow, Poland
2Center for Theranostics, Jagiellonian University, Krakow, Poland
*e-mail: neha.chug@doctoral.uj.edu.pl
The Jagiellonian Positron Emission Tomograph is the first plastic scintillator based tomographic device used to...
Authors: Romanò Sabrina, Flavio Di Giacinto, Riccardo Di Santo, Benedetta Niccolini, Alessandra Di Gaspare, Maria E. Temperini, Leonetta Baldassarre, Valeria Giliberti, Maria Vaccaro, Alberto Augello, Massimiliano Papi, Marco De Spirito, Michele Ortolani, Gabriele Ciasca
Extracellular Vesicles (EVs) are considered a promising source of cancer biomarkers. Despite this potential, the EV...
