9-11 October 2021
Theranostics Center / on-line
Europe/Warsaw timezone

Simulations of absorption in the brain of gamma quanta from positronium atoms

10 Oct 2021, 12:20
4h 10m
Theranostics Center / on-line

Theranostics Center / on-line

Kopernika 40 St. Kraków Poland
Board: 20

Speaker

Agata Jędruszczak

Description

Agata Jędruszczak for the J-PET collaboration
agatajedruszczak1999@gmail.com
Jagiellonian University in Kraków; Faculty of Physics, Astronomy and Applied Computer Science, Profesora Stanisława Łojasiewicza 11, 30-348 Kraków

The poster shows the results of the research on the absorption in the brain of gamma quanta from positronium atoms created during the PET imaging.
Positronium imaging [1] is a new imaging method that allows to determine not only the location of the tumor, but also the degree of its malignancy [2]. It is the multi-photon imaging, which uses not only 2𝜸, but also 3𝜸 annihilations. Amount of detected photons from decay into 2𝜸 or 3𝜸 give information about tissue structure. Moreover, the 3𝜸/2𝜸 ratio allows the description of neoplastic changes [3]. The brain in these studies is approximated by a sphere with water. Monte Carlo simulations of positron decays and photon absorption in the brain and skull were performed. The simulation results were compared with theoretical calculations. The results of the percent events for which none of photons scattered in the head are as follows: 26.10 ± 0.05 % for para-positronium and 8.40 ± 0.03 % for ortho-positronium (absorption in the brain), 20.84 ± 0.05 % for para-positronium, 5.46 ± 0.02 % for ortho-positronium (absorption in the brain and in skull). The values of the ratio from the simulation are: 0.322 ± 0.002 for absorption in the brain and 0.262 ± 0.002 for absorption in the brain and skull. The dependence of absorption probability of photons in the head on the location of positronium atom decay in the brain is determined.
The poster will present the above-mentioned results and plots obtained in the simulations. The methods by which the simulation results were obtained will also be presented.
References
[1] P. Moskal et al., "Positronium imaging with the novel multi-photon PET scanner", Science Advances (in press)
[2] P. Moskal, D. Kisielewska, C. Curceanu et al., "Feasibility study of the positronium imaging with the J-PET tomograph",Phys. Med. Biol. 64:055017 (2019)
[3] B. Jasińska, P. Moskal, "A New PET Diagnostic Indicator Based on the Ratio of 3𝜸/2𝜸 Positron Annihilation",Acta Phys. Pol. B,48:1577-1582 (2017).

Primary author

Agata Jędruszczak

Presentation Materials