In radiation oncology and nuclear medicine, the efficacy of theranostic strategies (i.e. combining treatment with diagnostic imaging) may be dramatically improved by leveraging the unique properties of nanoparticles. Due to their nanoscale size, nanoparticles can penetrate target tissues and tumour cells, and enhance physico-chemical reaction rates. In this talk, I will discuss the...
Among many computational methods, compartmental models are still attractive for many applications in medicine, both in the fields of therapy and diagnosis. Below relevant examples are presented, they are based on literature and own research results.
Kinetics models based on differential equations are common for dose estimation in extracorporeal therapies. Hemodialysis adequacy considers...
One of the most important challenges in modern medicine is to ensure the desired course of delivery of active pharmaceutical ingredients (APIs) to the patient’s body. Therefore, many studies are devoted to new delivery systems that can control both rate and period of drug delivery as well as the place of their administration. An important factor to consider when designing controlled release...
Delivering of the active pharmaceutical ingredients (APIs) to the organism in the desired manner is a great challenge. Therefore, it is important to develop and investigate new systems, allowing to control both the rate and the period of drug delivery. In such systems, the carrier, in which API is dissolved, can and should be designed and/or modified in a way which allows to control the...
Designed proteins offer us the potential of matching or exceeding the capabilities of nature’s own naturally-occurring protein nanomachines which demonstrate a wonderous array of properties. Protein cages are hollow, typically spherical nanoscale protein assemblies which in nature have multiple uses such as materials storage, genome delivery (viruses) and catalysis (enzymes). As such it is...
