PET and SPECT are truly translational since the same methods can be applied in animals and in clinical studies. Owing to the small structures, dedicated instrumentation is needed for mouse and rat imaging, while large animal models can be investigated using clinical systems. Some new detector concepts have been introduced first in preclinical systems before scaling up to clinical systems....
Designed proteins offer us the potential of matching or exceeding the capabilities of nature’s own naturally-occurring protein nanomachines which demonstrate a wonderous array of properties. Protein cages are hollow, typically spherical nanoscale protein assemblies which in nature have multiple uses such as materials storage, genome delivery (viruses) and catalysis (enzymes). As such it is...
Bialystok Center of Molecular Imaging (BCMI) is one of the key elements of the new project of the Innovative Research Center for the Prevention of Civilization Diseases and Individualized Medicine (CBI PLUS), that is now proceeding by the Medical University of Bialystok (MUB). This will be the first laboratory for the synthesis and quality control of radiopharmaceuticals in the region and the...
Cargo carried by extracellular vesicles (EVs) is considered as a promising diagnostic marker, especially proteins [1,2]. EVs can be divided according to their size and way of biogenesis into exosomes (diameter <200 nm) and ectosomes (diameter <200 nm) [1].
First step of this study was characterization of EVs sample [2]. Using Tunable Resistive Pulse Sensing (qNano) size distribution and...