At present, Boron Neutron Capture Therapy (BNCT) is considered to be a promising method for the treatment of tumors. The report presents the basics of BNCT, its development stages, the state of development of accelerator neutron sources for BNCT clinics and describes in detail the Novosibirsk accelerator neutron source. This source is a state-of-the-art device comprised of i) the Vacuum...
Polish R&D program for Boron Neutron Capture Therapy (BNCT) started in 2001 and is presently coordinated by the National Centre for Nuclear Research (NCBJ) at Świerk/Otwock. The program aims to put in operation the dedicated research BNCT beam line at Maria reactor at Świerk and to offer this beam for R&D related to BNCT. At present, the interest of physicians in the project is limited since...
Damian Kaniowski,a Katarzyna Ebenryter-Olbińska,a Katarzyna Kulik,a Slawomir Janczak,b Anna Maciaszek,a Katarzyna Bednarska-Szczepaniak,b Barbara Nawrota and Zbigniew J. Leśnikowskib
aCentre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland; bInstitute of Medical Biology, Polish Academy of Sciences, Lodowa 106 92-232, Lodz,...
Carcinogenesis is a process providing cell DNA changes. As a consequence, cells begin to divide rapidly. The cancerous tissue growth requires an increased supply of nutrients and oxygen therefore the tumor needs to produce its own irregular blood vessels network. Combating pathological angiogenesis is one of the basic strategies of anticancer therapy.
There are a few methods capable of...
An evaluation of the design of BSA for BNCT is discussed based on GEANT4 simulations. To create the realistic model by GEANT4 program there are inserted two physics lists for nuclear and electromagnetic reactions. The feasibility study describes the thermalization of neutrons from two different neutron sources based on DD, DT compact neutron generators.
In some cases, a multiplier, based on...
