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SUMMARY:Invited talk: Towards High Sensitivity and High-Resolution PET Sca
 nners\; Image-guided Proton Therapy and Total Body imaging
DTSTART;VALUE=DATE-TIME:20220713T140500Z
DTEND;VALUE=DATE-TIME:20220713T142500Z
DTSTAMP;VALUE=DATE-TIME:20260720T195310Z
UID:indico-contribution-48-729@indico.koza.if.uj.edu.pl
DESCRIPTION:Speakers: Karol Lang\; University of Texas at Austin\, USA ()\
 nhttps://indico.koza.if.uj.edu.pl/event/7/contributions/729/
LOCATION:Collegium Novodvorscianum
URL:https://indico.koza.if.uj.edu.pl/event/7/contributions/729/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Polarization and directional correlations of γ-rays for nuclei: S
 cope in PET
DTSTART;VALUE=DATE-TIME:20220713T142500Z
DTEND;VALUE=DATE-TIME:20220713T144500Z
DTSTAMP;VALUE=DATE-TIME:20260720T195310Z
UID:indico-contribution-48-693@indico.koza.if.uj.edu.pl
DESCRIPTION:Speakers: Pragya Das\; Indian Institute of Technology Bombay\,
  India ()\nThe spectroscopic investigation of nuclei at high spin states h
 as led to many discoveries\, e.g.\, exotic shapes\, super-deformation\, sh
 ape coexistence\, and chiral symmetry. In this endeavor\, the accurate spi
 n-parity assignment to nuclear states is crucial. Many studies in the lite
 rature have focused on finding the directional correlation ratios (DCO) fo
 r the assigning spins without any polarization measurement for parity dete
 rmination. The use of polarization-directional correlation (PDCO) [1] not 
 only determines the parity\, but can also easily distinguish stretched and
  non-stretched γ-transitions\, allowing to establish both spin and parity
 . We have confirmed some earlier tentative spin-parities in 128I and 129Xe
  and modified a few of them with our new results on mixing ratios using PD
 CO. It is needless to mention here that a fresh understanding of the nucle
 ar structure is required if the spin-parity of the bandhead state is chang
 ed.\nWe performed an experiment via the fusion-evaporation reaction – 11
 B (124Sn\; α3n\, p5n) 128I\, 129Xe – using the Pelletron accelerator at
  the Tata Institute of Fundamental Research (Mumbai\, India). The experime
 ntal set-up (INGA) consisted of 21 Compton suppressed HPGe clover detector
 s. The list-mode data [2] were utilized to construct the asymmetric matrix
  for finding PDCO. We used 90∘ detectors as polarimeters (θpil) and all
  other detectors as directional detectors (θdir)\, and followed the PDCO 
 formalism by Droste et al. [1].\nFor the case of 129Xe\, we assigned [3] t
 he bandhead spin-parity 21/2+ to a 2180 keV state decaying via 604 keV γ-
 ray\, based on only the DCO information. Our finding (21/2+) and other ava
 ilable results for the same state – 19/2+ by Huang et al. [4] and 19/2
 – by Helppi et al. [5] – were all in complete disagreement. So\, it be
 came imperative to confirm our assignment by further analyzing the PDCO da
 ta\, which enabled us to establish the same state 21/2+. Moreover\, there 
 were other discrepancies\, and we could resolve them by critically examini
 ng the PDCO contour plots\, i.e.\, polarization (P) vs. DCO ratios (RDCO) 
 for different values of mixing ratios. It was possible to distinguish stre
 tched and non-stretched transitions. Notably\, no polarization measurement
  existed in the literature prior to our work.\nIn the context of using pol
 arization correlation of coincident γ-rays\, the property of entanglement
  (orthogonal polarization) of annihilation photons (511 keV) has immense p
 otential in positron emission tomography (PET). It can help classify the t
 rue coincidence events amongst the scattered\, random\, and multiple event
 s. However\, the research area has not been fully explored\, probably beca
 use of experimental difficulties. Only a few simulation-based studies exis
 t [6\, 7]. We have also tried a preliminary study [8] with many simplified
  assumptions but have not yet succeeded in improving the image quality.\n\
 n[1] Ch. Droste et al.\, Nucl. Instr. Meth. Nucl. Res. A 378 (1996) 518.\n
 [2] U. Lamani et al.\, Nucl. Phys. A 1014 (2021) 122220.\n[3] V. K. Pasi e
 t al.\, JPS Conf. Proc. 6 (2015) 030016.\n[4] Y. Huang et al.\, Phys. Rev.
  C 93\, (2016) 064315.\n[5] H. Helppi et al.\, Nucl. Phys. A 357 (1981) 33
 3.\n[6] A. L. McNamara et al.\, Phys. Med. Biol. 59 (2014) 7587.\n[7] M To
 ghyani et al.\, Phys. Med. Biol. 61 (2016) 5803.\n[8] Satyajit Ghosh\, Ph.
  D. thesis submitted (2022)\, IIT Bombay\, India.\n\nhttps://indico.koza.i
 f.uj.edu.pl/event/7/contributions/693/
LOCATION:Collegium Novodvorscianum
URL:https://indico.koza.if.uj.edu.pl/event/7/contributions/693/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Invited talk: Multi-isotope imaging and quantum chemical sensing w
 ith PET and SPECT nuclides
DTSTART;VALUE=DATE-TIME:20220713T134500Z
DTEND;VALUE=DATE-TIME:20220713T140500Z
DTSTAMP;VALUE=DATE-TIME:20260720T195310Z
UID:indico-contribution-48-692@indico.koza.if.uj.edu.pl
DESCRIPTION:Speakers: Kenji Shimazoe\; The University of Tokyo\, Japan ()\
 nMulti-isotope imaging is important for investigating multi-molecule dynam
 ics in individuals. PET and SPECT dual tracer imaging in vivo is demonstra
 ted with a developed Compton PET hybrid camera. In nuclear medicine imagin
 g\, quantum chemical sensing\, such as pH and chemical state of molecule\,
  can be additional value to accumulation imaging. pH sensing and imaging i
 s demonstrated with liquid state In-111 SPECT nuclide by double-photon ima
 ging method. Recent works on multi-isotope imaging and quantum sensing wit
 h double photon imaging will be introduced.\n\nhttps://indico.koza.if.uj.e
 du.pl/event/7/contributions/692/
LOCATION:Collegium Novodvorscianum
URL:https://indico.koza.if.uj.edu.pl/event/7/contributions/692/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Key talk: PET imaging innovations
DTSTART;VALUE=DATE-TIME:20220713T132000Z
DTEND;VALUE=DATE-TIME:20220713T134500Z
DTSTAMP;VALUE=DATE-TIME:20260720T195310Z
UID:indico-contribution-48-691@indico.koza.if.uj.edu.pl
DESCRIPTION:Speakers: Taiga Yamaya\; National Institutes for Quantum and R
 adiological Science and Technology (QST)\, Japan ()\nIn current PET\, only
  a few percent of gamma rays emitted from a patient are used for imaging. 
 Therefore\, improvement of the sensitivity is a hot topic worldwide. Axial
  extension\, which is referred as total-body PET\, is essential in terms o
 f the sensitivity improvement. In organ dedicated imaging\, on the other h
 and\, it is possible to improve the sensitivity without increasing the num
 ber of detectors. Improvement of spatial resolution is also expected by el
 iminating the photon non-collinearity effect.\nIn the former part of this 
 presentation\, development of brain-dedicated PET systems will be reviewed
 . Among them\, we have recently developed VRAIN\, a PET system with a hemi
 spherical detector arrangement [1]. The hemispherical geometry fits the he
 ad best\, and minimizes the photon non-collinearity effect by reducing the
  detector-to-detector distance.\nIn the latter part of the presentation\, 
 alternative approaches to improve the sensitivity rather than increasing t
 he solid angle of the measurement system will be reviewed. Among them\, wh
 ole gamma imaging (WGI) is a novel concept of combined PET with Compton im
 aging. An additional detector ring\, which is used as the scatterer\, is i
 nserted in a conventional PET ring so that single gamma rays can be detect
 ed by the Compton imaging method. In addition to conventional PET and Comp
 ton imaging\, further large impact can be expected for triple gamma emitte
 rs such as Sc-44 (~4 h half-life)\, that emits a positron and a 1157 keV g
 amma ray almost at the same time. In principle\, only a few decays would b
 e enough to localize the source position by calculating intersection point
 s of a 511 keV line-of-response with a 1157 keV Compton cone. We developed
  a prototype of the WGI system [2][3]\, and a Na-22 point source\, which e
 mits a 1275 keV gamma ray soon after a positron decay\, was measured as an
  alternative to Sc-44. In the triple gamma imaging\, where only simple bac
 kprojection was applied and no image reconstruction algorithm was applied\
 , spatial resolution for the Na-22 point source was 4.8 mm FWHM (8 cm off-
 center) - 5.7 mm FWHM (center). WGI can be also used to measure positroniu
 m lifetime [4]\, which may enable a new field of “quantum PET (Q-PET)”
 . One possible application of Q-PET is hypoxia imaging of tumor patients [
 5].\n\n[1] E. Yoshida\, Hideaki Tashima\, Go Akamatsu\, et al.\, “245 ps
 -TOF brain-dedicated PET prototype with a hemispherical detector arrangeme
 nt\,” Phys. Med. Biol.\, 65\, 145008\, 2020.\n[2] E. Yoshida\, H. Tashim
 a\, K. Nagatsu\, et al.\, "Whole gamma imaging: a new concept of PET combi
 ned with Compton imaging\," Phys. Med. Biol.\, 65\, 125013\, 2020.\n[3] H.
  Tashima\, E. Yoshida\, H. Wakizaka\, et al.\, "3D Compton image reconstru
 ction method for whole gamma imaging\," Phys. Med. Biol.\, 65\, 225038\, 2
 020.\n[4] P. Moskal\, B. Jasińska\, E.Ł. Stępień\, et al.\, “Positro
 nium in medicine and biology\,” Nat. Rev. Phys. 1\, 527-529\, 2019.\n[5]
  K. Shibuya\, H. Saito\, F. Nishikido\, et al.\, "Oxygen sensing ability o
 f positronium atom for tumor hypoxia imaging\," Commun. Phys. 3\, 173\, 20
 20.\n\nhttps://indico.koza.if.uj.edu.pl/event/7/contributions/691/
LOCATION:Collegium Novodvorscianum
URL:https://indico.koza.if.uj.edu.pl/event/7/contributions/691/
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